… to metabolic diseases (Figure 1). Here, we introduce myokines, adipokines and hepatokines
… mechanism that allows communication amongst metabolic organs in the endocrine system. …

… adipokines, myokines and hepatokines likely act in concert and drive many of the long-term
metabolic … The metabolic improvements observed in the muscle might relate to reduction of …

… changes leading to obesity and its metabolic consequences, … crosstalk among adipokines,
myokines, and hepatokines to … cardiovascular diseases and metabolic disorders. To the best …

… known to directly affect glucose and lipid metabolism. In analogy to the functional proteins
… adipokines and myokines—these liver-derived proteins are known as hepatokines. The first …

… adipokines along with traditional adipokines. We have briefly summarized pathological
changes in adipokine … significance of adipokines as therapeutic targets for obesity and T2DM (…

… to metabolic adaptations in a number of distinct organs. … also act on the liver although the
release of hepatokines during … and osteoprotegerin (type II muscle-specific myokines) was …

… have recently gained greater attention as regulators of metabolic diseases (14). … of
adipokines, hepatokines, and myokines in the regulation of AT inflammation and related metabolic …

… , including hepatokines, myokines, and adipokines, in the … of irisin in exercise-induced
metabolic adaptation [90]. Following the … in individuals with obesity, type II diabetes, and insulin …

… Metabolic energy demands may also be met through redistribution of energy substrates
due to increased SkM mass with oxidative metabolic adaptations that allow for enhanced …

… In 2016, we published the so-called adipokine–myokine–hepatokine compartment model
[108]. Based on the knowledge at the time, the interrelations between skeletal muscle mass, …